Avanafil (Stendra)

Overview of Avanafil (Stendra)

Avanafil is the generic name of the product. It is marketed under the brand name Stendra. It is one of the most popular medicines for men’s health. This medication treats erectile dysfunction (ED) in men. It helps men achieve and maintain an erection sufficient for sexual activity. As a newer ED medication, it offers faster onset and fewer side effects compared to older drugs.

How Does Avanafil Work?

Avanafil is a phosphodiesterase type 5 (PDE5) inhibitor. These medications prevent an enzyme called phosphodiesterase type-5 from working too quickly. This enzyme is found in the penis. When a man feels sexually excited, his body responds by sending more blood to the penis, which leads to an erection. However, the phosphodiesterase type-5 enzyme can break down this process too soon.

Avanafil helps keep the increased blood flow to the penis after sexual stimulation. It allows the erection to last longer. It’s important to know that Avanafil won’t cause an erection by itself. Physical sexual arousal and stimulation, such as during sexual activity, are needed for it to work.

In simple terms, Avanafil helps achieve and maintain an erection by controlling an enzyme that can block the natural increase of blood flow to the penis during sexual intercourse. However, it requires physical and sexual stimulation to initiate the process.

Uses

  • Avanafil is primarily approved for the treatment of erectile dysfunction (ED) in men. ED is a common condition affecting millions of men worldwide. It means not being able to get or keep an erection sufficient for sexual intercourse.
  • Avana pills are also effective in improving erectile function in men.
  • It is usually prescribed when physical factors cause ED—for example, cardiovascular disease, diabetes, or nerve disorders.
  • This drug is not officially approved for other uses. However, some healthcare providers may prescribe Avanafil off-label for conditions like pulmonary arterial hypertension or Raynaud’s phenomenon. More research is needed to understand these uses better.

Avanafil Medications Under Stendra Brand

Dosage and Administration

Avanafil is available in various dosages. The strength of these medicines is that they are 50 mg, 100 mg, super 160mg, and 200 mg. Usually, doctors recommend starting the dose with 100 mg. Take as needed, about 15-30 minutes before engaging in sexual activity.

It can be taken with or without food. However, taking it on an empty stomach may result in a faster onset of action.

The dose can be adjusted based on how well it works and how well you tolerate it. Doctors or healthcare providers will adjust the dosage by considering your health conditions.

Storage

You should store Stendra at room temperature. You also need to keep it away from moisture and heat, and out of reach of children.

Side Effects of Avanafil

Though Avanafil Stendra is one of the latest treatments for ED, it also has side effects. In fact, all the ed drugs are not free from side effects. But you need to consult with doctors for the most suitable medication. Here are some side effects,

Common Side Effects:

  • Headache
  • Flushing
  • Nasal Congestion
  • Back Pain

Less Common Side Effects:

  • Dizziness
  • Nausea
  • Cold Symptoms

Serious Side Effects:

  • Vision Changes
  • Hearing Loss:
  • Priapism
  • Chest Pain

Allergic Reactions:

  • Rash
  • Swelling
  • Breathing Difficulties

What to Do if You Experience Side Effects

Mild Side Effects: If you experience mild side effects. They often go away on their own. If they persist or bother you, contact your healthcare provider.
Serious Side Effects: If you have severe or worrying side effects, get medical help immediately.

Important Notes

  • Always consult your healthcare provider before starting Avanafil to discuss potential side effects. He will ensure that it is safe or unsafe.
  • Let your doctor know if you have any pre-existing conditions or medications to avoid harmful interactions.

Drug Interactions

Avanafil can interact with a variety of medications, diseases, and even food. The effects of either Avanafil or the other drug may change and cause potential problems.

Nitrates (e.g., nitroglycerin, isosorbide dinitrate, isosorbide mononitrate)

Effects: Combining Avanafil with nitrates can lead to a significant drop in blood pressure. It will result in dizziness, fainting, or even a heart attack or stroke.

Alpha-Blockers (e.g., doxazosin, tamsulosin)

Effect: Both avanafil and alpha-blockers lower blood pressure. Taking them together can cause an additive effect. It may lead to hypotension (low blood pressure) and related symptoms like dizziness or fainting.

Erectile Dysfunction Medications containing PDE5 Inhibitors (e.g.,
sildenafil/viagra, tadalafil/Cialis, Vardenafil)

Effect: Taking multiple ED medications together can cause more side effects. But it won’t help them work better.

Strong CYP3A4 Inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)

Effect: These medications can increase the levels of Avanafil in the blood.

Blood Pressure Medications, Antihypertensive Drugs (e.g., amlodipine, ACE inhibitors, ARBs)

Effect: Taking Avanafil along with certain other drugs can cause your blood pressure to drop too low.

Alcohol

Effect: Alcohol can increase the risk of side effects such as dizziness, Headache, and low blood pressure.

When using Avanafil, it is vital to be aware of potential drug interactions. Always consult your healthcare provider before starting, stopping, or combining it with other medications.

Precautions and Warnings

  • Avoid using Avanafil if you are taking nitrates.
  • If on alpha-blockers, consult your doctor, who may adjust the dose or timing.
  • Do not combine Avanafil with other PDE5 inhibitors.
  • Monitor blood pressure regularly and consult with your healthcare provider for dose adjustments.
  • Limit alcohol intake when taking Avanafil.
  • Men who recently had a heart attack, stroke, or irregular heartbeat in the past six months should avoid taking Avanafil.
  • Consult your healthcare provider. Let him know your previous health conditions and medications.
  • Inform your doctor if you face any side effects.

Comparison with other ED Medications

Avanafil (Stendra) vs Sildenafil (Viagra)

Avanafil is one of the latest ed drugs. The approval year of Avanafil is 2012 whereas Sildenafil was approved in 1998. That’s why Viagra is one of the well-researched and known ED pills. The onset of action is faster in the case of Stendra. It takes 15-30 minutes. On the other hand, Viagra takes 30-60 minutes. Both medications have almost the same duration of effect. Avanafil is less affected by food whereas high-fat meals reduce the efficacy of Sildenafil.

Avanafil (Stendra) vs Tadalafil (Cialis)

Tadalafil got approval in 2003 which is a long time ago of Avanafil. The onset of action is slightly slower in the Cialis. It takes 30-45 minutes. The duration of Tadalafil’s action (up to 36 hours ) is much longer than that of Avana pills. Tadalafil is only mildly to moderately affected by alcohol, whereas Avanafil is moderately affected by alcohol.

Avanafil (Stendra) vs Vardenafil (Levitra, Staxyn)

Vardenafil got approval in 2003 which was a long time ago of Stendra. Avanafil is less impacted by food intake, while high-fat meals can reduce the effectiveness of Vardenafil. One advantage of Staxyn is that it is available in ODT form for those who have difficulty swallowing pills.

 

Frequently Asked Questions (FAQs)

What is Avanafil used for?

Doctors prescribe Avanafil for the treatment of erectile dysfunction (ED). Avanafil helps men get and keep an erection by increasing blood flow to the penis during sexual activity.

How long does Stendra/Avanafil last?

The effects of Stendra Avanafil can last up to 6 hours. The peak effect occurs within the first 2 hours after taking it.

How much does Avanafil cost?

The cost of Avanafil varies depending on the pharmacy, location, strengths, dosage, and many other factors. It can also vary in both offline and online pharmacies. Sunshine RX Pharmacy is one of the best online pharmacies in the USA. You can buy generic Stendra online without prescriptions from our online medical store.

Where can I buy Avanafil online?

You can order Avanafil online from various pharmacies. There are a lot of online medical stores offering medications. You may also ask if it is safe to buy generic Stendra online. Yes, buying from a licensed and reputable online pharmacy is safe. You need to ensure the pharmacy is trusted and reputable. Justify the reviews of the store before purchasing from an online store. Sunshine RX Pharmacy is a trusted online medical store. You can buy ED medications from this store at the cheapest prices.

How long does it take for Avanafil to work?

Avanafil (Stendra) starts working within 15 to 30 minutes after ingestion. Its effects can last up to six hours. And it is relatively fast compared to other ED medications.

Is Avanafil safe for everyone?

Avanafil may not be suitable for individuals. Everyone has different medical conditions, such as severe heart or liver problems, recent stroke or heart attack, low blood pressure, or particular eye conditions. It’s essential to consult with a healthcare provider before using Avanafil. Remember that your good health is the priority.

What is the difference between Avanafil and other ED medications like Sildenafil, Tadalafil, or Vardenafil?

Avanafil, Sildenafil (Viagra), Tadalafil (Cialis), and Vardenafil (Levitra) are all PDE5 inhibitors used to treat ED. The primary differences lie in their onset of action and duration.

Avanafil starts working fast, in just 15 minutes. Viagra and Vardenafil take longer, at 30-60 minutes, before they start working. However, Cialis lasts much longer in the body – up to 36 hours. Avanafil only lasts for 6 hours. So Avanafil works quicker than Viagra/Vardenafil but doesn’t last as long as Cialis. Its effects are somewhere in the middle regarding how long they last.

Can women take Avanafil?

Avanafil is not approved for use in women. The effects of this have not been extensively studied in women. It is specifically designed to treat men’s impotence.

What should I do if Avanafil does not work for me?

If Avanafil does not produce the desired results, speaking with a healthcare provider is essential. They may adjust the dosage or suggest trying a different ED medication.

Is Avanafil available over the counter?

Avanafil is a prescription medication and is not usually available over the counter. We won’t encourage you to take the ed drugs without evaluation by a doctor. The healthcare provider will determine if Avanafil is appropriate for you. Once a doctor advises you, you can buy Avanafil online from many online pharmacies.

What should I do if I experience severe side effects from Avanafil?

If you experience severe side effects such as sudden vision loss, hearing loss, or an erection lasting more than four hours (priapism), consult with your doctor immediately. These conditions can cause permanent damage if not treated.

Can Avanafil be used recreationally?

We will not recommend using Avanafil recreationally without a prescription and medical supervision. Misusing it or without a medical need can cause serious harm to your health.

Are there any dietary restrictions when taking Avanafil?
There are no strict dietary restrictions. However, it is advised to avoid heavy or high-fat meals before taking Avanafil, as these can slow down the medication’s absorption and reduce its effectiveness.

Can you take Stendra and Viagra together?

No, you should not take Stendra and Viagra together. Taking these drugs together can cause very serious side effects.

Which is better, tadalafil or Avanafil?

Both medications are effective for ED, but they differ in onset and duration of action. Tadalafil lasts longer (up to 36 hours), while Avanafil acts faster.

Is Avanafil more potent than Viagra?

Avanafil and Viagra are both effective PDE5 inhibitors. However, their effectiveness can vary depending on the individual. Avanafil works faster, while Viagra has a longer track record.